Recent findings in immune monitoring for HGG patients treated with autologous DC vaccination: CD127 expression inversely correlates with Foxp3 and suppressive function of CD4+ Treg cells

H. Ardon, W. Maes, T. Beez, S. Van Gool & S. De Vleeschouwer
Objective: We have successfully treated over two hundred high-grade glioma (HGG) patients with adjuvant immunotherapy consisting of vaccination with autologous dendritic cells (DC) loaded with autologous tumor lysate. It has recently been shown that regulatory T cells (Treg) play an important role in[for full text, please go to the a.m. URL]