Reactivation of cell death by -/- gossypol in apoptosis-resistant malignant glioma

V. Voss, D. Kögel, C. Senft, H. Hetschko & V. Seifert
Objective: Anti-apoptotic Bcl-2 family members play a fundamental role for the therapy resistance of malignant gliomas, and are known to regulate both apoptosis and autophagy. Here, we correlated expression levels of Bcl-2 family members with the inherent cell death resistance of glioma cell lines and[for full text, please go to the a.m. URL]