ALA-PDT induced cell death in malignant gliomas – mechanisms of action

P. Slotty, N. Etminan, C. Peters, H.-J. Steiger & W. Stummer
Objective: ALA-PDT (delta-aminolevulinic acid supported photodynamic therapy) is a method under investigation for its benefit on survival in recurrent gliomas. Exact cellular mechanisms are not well understood so far. We investigated the mechanisms of damage and induction of apoptosis by photodynamic[for full text, please go to the a.m. URL]