The expression of glutamate and NMDAR1 correlates with WHO grade and is up-regulated at the tumor-brain-interface

J. Walter, S. Kuhn, A. Fisker & R. Kalff
Objective: Recent studies showed that human glioma cells secrete glutamate, by which their growth was increased. This proliferation facilitation was explained by a glioma-brain interaction. Blockade of NMDA-receptors led to a reduction of glioma growth. In this study the expression of glutamate and [for full text, please go to the a.m. URL]