The influence of pellet density on the graft-induced functional recovery in a skilled paw-reaching test in the rodent unilateral 6-OHDA Parkinson's disease model

K. Kohn Cordeiro, A. Papazoglou, W. Jang, O. Diaconu, M. Döbrössy & G. Nikkhah
Objective: A rat model of Parkinson’s disease (PD) is based on unilateral injections of 6-OHDA into the medial forebrain bundle (MFB) of the rat, resulting in a complete loss of nigral dopamin­ergic neurons and leading to a depletion of dopamine (DA) within the striatum inducing motor deficits.[for full text, please go to the a.m. URL]