Low grade glioma invasion is dependent on microglia

D. Markovic, C. Sridhar, S. Michael, K. Jürgen, G. Rainer & K. Helmut
Objective: We have shown previously that the microglia surrounding glioma is promoting glioma invasiveness by activation of MMP-2 (Markovic et al. 2005). Now we investigate whether microglial expression of membrane type 1 metalloprotease (MT1-MMP) is regulated by gliomas. Methods: We used immunohistochemistry,[for full text, please go to the a.m. URL]