Egr-1 is not regulated under hypoxic conditions in human glioblastoma

H. Said, C. Hagemann, B. Polat, M. Flentje, G. Vince & D. Vordermark
Objective: It has been shown in several publications (Ellen T et al., 2007; Zhang P et al., 2007) that the transcription factor Egr-1 is regulated via hypoxia, and the authors hypothesized that Egr-1 is responsible for hypoxia induced NDRG1 gene regulation in human tumor cells. HIF-1α is the main[for full text, please go to the a.m. URL]