Inhibition of vincristine cytotoxicity by blocking glucose transporter 1 in human glioblastoma cell lines

F. Stockhammer, A. Elstner & A. Von Deimling
Objective: Vincristine (VCR) is a widely used cytostatic agent in malignant gliomas. Due to its hydrophilic properties cellular uptake depends on transport. In gliomas this transport has not been studied up to now. However, in other cancers glucose transporter 1 (GLUT1) was identified to accomplish [for full text, please go to the a.m. URL]