Role for soluble fibrinogen to inhibit neutrophil adhesion and sequestration after trauma

J. Pillay, V. Kamp, L. Leenen, L. Koenderman & L. Ulfman
Problem: Soluble fibrinogen (sFg) is an acute phase protein. In inflammation e.g. following trauma it increases up to 10 mg/ml. Complications after trauma such as ARDS and MOF are mediated by neutrophils through adhesion to endothelial cells (EC) or sequestration in the vasculature: Adhesion-molecule[for full text, please go to the a.m. URL]