Towards an intraoperative engineering of osteogenic grafts from the stromal vascular fraction of human adipose tissue

A. Mehrkens, A. M. Müller, D. J. Schaefer, M. Jakob, I. Martin & A. Scherberich
Problem: To evaluate the feasibility of an intraoperative approach to engineer cell-based bone grafts with tissue harvest, cell-isolation, cell-seeding in the scaffold and subsequent implantation within a few hours. Mesenchymal and endothelial lineage cells isolated from the stromal vascular fraction[for full text, please go to the a.m. URL]