Distinct sphere types generated from cochlear sensory epithelium-derived stem cells

Marc Diensthuber, Kazuo Oshima, Timo Stöver, Thomas Lenarz & Stefan Heller
Birds, fish and amphibians replace lost sensory hair cells by asymmetric division of supporting cells which serve as bona fide stem cells resulting in high regenerative capacity of hair cell-bearing organs. In contrast, hair cell regeneration does not occur in the mammalian inner ear, but cells with[for full text, please go to the a.m. URL]