Geldanamycin induces heat shock protein 70 (HSP70) production in the organ of Corti and protects against gentamicin ototoxicity

Agnes Szczepek, Heidemarie Haupt, Timo Stöver & Birgit Mazurek
Introduction: Induction of HSP70 in inner ear protects against various ototoxic conditions. Here, we tested the ability of geldanamycin and resveratrol to induce HSP70 in the organ of Corti (OC). Furthermore, we determined the protective effect of pahrmacologically induced HSP70 against ototoxicity [for full text, please go to the a.m. URL]