Analysis of Toll-like Receptor-2 (TLR2) Polymorphisms in chronic Rhinosinusitis

Martin Wagenmann, Kathrin Scheckenbach, Matthias Hauer, Adam Chaker, Simone Hindersin & Jörg Schipper
Introduction: Toll-like Receptors (TLR) are key players in innate immunity. Because the expression of TLR2 and TLR4 is increased in chronic rhinosinusitis they could play an important role in this disease. It is known that the different expression of SNPs (Single Nucleotide Polymorphisms) of the TLRs[for full text, please go to the a.m. URL]