Effectiveness of protons in human prostate cell lines: the genetic background possibly determines the RBE in the Spread-out-bragg-peak compared to Plateau region

A. Staab, N. Frenzel, A. Coray, A. Lomax, R. Schneider, M. Pruschy & E. Hug
Background: Proton therapy is an effective therapy for localized prostate cancer. Even though a constant RBE of 1.1 is used in clinical routine there still exists an uncertainty regarding the relative biological effectiveness (RBE). The tumor suppressor protein p53 is considered to have an impact on[for full text, please go to the a.m. URL]