Graft preconditioning mit low-dose tacrolimus (FK506) and nitric oxide inhibitor aminoguanidine (AGH) reduces ischemia/reperfusion injury after liver transplantation in the rat

Edouard Matevossian, Dietrich Doll, Norbert Hüser, Volker Aßfalg & Stefan Thorban
Introduction: Ischemia/reperfusion (I/R) injury is a main cause of primary dysfunction or non-function after liver transplantation (LTx). The I/R inury is a multifactorial process that affects graft function after LTx. Recent evidence indicates that an increase in nitric oxide (NO) production[for full text, please go to the a.m. URL]