PAR-2 is a key regulator in the tissue factor/FVIIa pathway promoting migration and invasion of glioma cells

Florian Geßler, Stephan Dützmann, Valerie Voss, Volker Seifert, Rüdiger Gerlach & Donat Kögel
Objective: Malignant gliomas escape current treatment strategies by infiltrative growth and inevitable relapses of the tumor caused by residual tumor cells following resection. In gliomas, Tissue Factor (TF) expression is positively correlated with the grade of malignancy. Apart from its function in[for full text, please go to the a.m. URL]