Evaluation of the regeneration promoting potential of a 26-amino acid fragment of clostridium botulinum C3 protein in rat models of peripheral nerve regeneration

Kirsten Haastert, Annelie Handreck, Nele Korte, Claudia Grothe, Ingo Just & Stefanie C. Hülsenbeck
Objective: Recently it has been demonstrated that a C-terminal peptide fragment covering amino acid 154–182 of the Rho-inactivating C3 transferase (C3bot) from Clostridium botulinum, although transferase deficient, triggers dendritic and axonal growth and branching and increases synaptic connectivity[for full text, please go to the a.m. URL]