High frequency stimulation and pharmacological inactivation of the globus pallidus and the nucleus entopeduncularis differentially affect quinpirole-induced compulsive checking in rats

Anaïs Djodari-Irani, Julia Klein, Johann Banzhaf, Rudolf Morgenstern & Christine Winter
Objective: Deep brain stimulation (DBS) at high frequencies (HFS) is currently studied in the treatment of therapy-refractory obsessive compulsive disorders (OCD). The diversity of targeted brain areas used and the discrepancy in demonstrating beneficial effects, highlight the need for better mapping[for full text, please go to the a.m. URL]