Stem-like brain tumour initiating cells persist in established glioma cell lines

Christoph Richter, Christoph Schmitz-Salue, Margret Rave-Fraenk, Veit Rohde, Ella Kim & Alf Giese
Objective: Malignant brain tumours possess a hierarchy of cells differing in tumorigenic potential. Among the heterogeneous cell populations within the malignant glioma, so called Brain Tumour Initiating Cells (BTICs) are thought to be the most tumorigenic cellular compartment capable of re-populating[for full text, please go to the a.m. URL]