RNA interference targeting Survivin exerts anti-tumoral effects in vitro and in glioma xenografts

Sandy Hendruschk, Achim Aigner, Daniel Martin, Matthias Kirsch, Gabriele Schackert & Achim Temme
Objective: Despite multimodal treatments, the median survival of patients suffering from glioblastoma (GB) has not improved over the past decades. One promising approach to deal with GB is the inactivation of proteins essential for survival or progression by means of RNA interference (RNAi) techniques.[for full text, please go to the a.m. URL]