Attenuation of cell motility and invasion by treatment of U87 glioma cells with the nitric oxide donor JS-K in vitro

Stefanie Bette, Brunhilde Baumer & Astrid Weyerbrock
Objective: The diazeniumdiolate JS-K generates nitric oxide (NO) on enzymatic activation in GST-expressing cells. In addition to growth-inhibitory and chemosensitizing effects in tumors including U87 gliomas, JS-K has anti-invasive effects in breast cancer cells. The objective was to evaluate the anti-migratory[for full text, please go to the a.m. URL]