TFPI-2 acts as a tumor suppressor gene limiting cell proliferation, migration and invasion in glioma

Florian Geßler, Stephan Dützmann, Valerie Voss, Volker Seifert, Rüdiger Gerlach & Donat Kögel
Objective: Due to their invasive behaviour, malignant gliomas are currently an incurable disease. Malignant gliomas are chiefly of oligodendroglial or astrocytic origin and display large genetic alterations. Previous histological findings have demonstrated higher TFPI-2 expression levels in low grade[for full text, please go to the a.m. URL]