Expression changes of TP53-regulator PPM1D and Reprimo in atypical and anaplastic meningiomas

Shinjiro Fukami, Hans-Jacob Steiger, Guido Reifenberger & Markus J. Riemenschneider
Objective: Anaplastic meningiomas have a very sad prognosis with a median survival of under 2 years. Therefore, precise diagnosis and understanding of the biological behavior of anaplastic meningioma is very important. Nuclear immunoreactiviy of p53 protein has been detected in variable fractions of[for full text, please go to the a.m. URL]