The genome-wide transcriptional profiling of radioresistant stem-like brain tumour initiating cells

Alf Giese, Agatha Pilzak, Veit Rohde, Margret Rave-Fraenk, Walter Shulz-Schaeffer & Ella Kim
Objective: Stem-like Brain Tumour Initiating Cells (BTICs) appear to be a key cellular component of the invasive phenotype and resistance of malignant gliomas to radiotherapy. The molecular mechanisms of radioresistance in BTICs are largerly undefined. The aim of this study was to assess transcriptional[for full text, please go to the a.m. URL]