Downregulation of Wnt/β-catenin pathway in ACTH-secreting pituitary cell line AtT-20 by somatostatin

Muhammad Nasir Khan Khattak, Michael Buchfelder & Natalia Kremenevskaya
Objective: The Wnt/β-catenin signalling pathway plays a critical role in normal development as well as in tumorigenesis of various tissues including endocrines. We have shown previously that the Wnt/β-catenin pathway is dysregulated in adrenocorticotropin (ACTH)-secreting pituitary[for full text, please go to the a.m. URL]