Analysis of p75NTR in medulloblastoma

Jan Küchler, Wolfgang Hartmann, Volker Tronnier & Thorsten Pietsch
Objective: The classic (CMB) and the desmoplastic (DMB) subtypes represent the major medulloblastoma variants. In contrast to CMB, DMB display high levels of the low-affinity nerve growth factor receptor p75NTR. Apoptotic and proliferative functions have been attributed to p75NTR. Given reports of a[for full text, please go to the a.m. URL]