Spreading depolarizations in clusters affect cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage

Edgar Santos, Alexandra Nagel, Kara L. Krawenski, Daniel Hertle, Asita S. Sarrafzadeh, Jens P. Dreier, Andreas Unterberg & Oliver W. Sakowitz
Objective: Spreading depolarizations (SDs) contribute to infarct expansion in experimental brain injury. SDs also propagate in the injured human brain, whether they contribute to secondary brain damage is not clear yet. Cerebral microdialysis may be used to assess metabolic changes in patients with [for full text, please go to the a.m. URL]