Tumorigenicity of ES cell derived neural precursors in a model of spinal cord injury

K. Hakan Sitoci-Ficici, Andrea Meinhardt, Elke Leipnitz, Robert Later, Daniel K. Martin, Kathrin Geiger, Gabriele Schackert, Elly M. Tanaka & Matthias Kirsch
Objective: Current experimental therapies for spinal cord injury (SCI) include focal application of neurotrophic factors, biocompatible materials, and cellular transplantation. Recently, we engineered neural-tube-like neuroepithelial cells (NEC) from mouse embryonic stem cells (ESC). NEC are capable[for full text, please go to the a.m. URL]