Myoblast-mediated gene therapy via encephalomyosynangiosis – a novel strategy for local delivery of angiogenic factors to the brain surface

Nils Hecht, Melina Nieminen-Kelhä, Irina Kremenetskaia, Johannes Woitzik, Helen Blau & Peter Vajkoczy
Objective: For the prevention of stroke in chronic cerebral ischemia, myoblast-mediated gene transfer via an encephalomyosynangiosis (EMS) may represent an innovative approach to augment therapeutic angiogenesis in the brain. The aim of the present study was to test the effect of an EMS with and without[for full text, please go to the a.m. URL]