Donor age dependent graft development and recovery in a rat model of Huntington's disease: Cellular and behavioural analysis

Steffi Schackel, Anita Papazoglou, Robert Kirch, Guido Nikkhah & Máté Döbrössy
Objective: Clinical trials of fetal striatal grafts in HD patients have so far shown a range of outcomes from no effect to disease modifying capability. Amongst the many variables involved is the age of the donor embryo at the time of grafting. In this study we aim to shed more light on how embryonic[for full text, please go to the a.m. URL]