Improving Femoral Defect Healing in Rats by Modification of BMP Inhibition

B. Willie, H. Schell, C. Schwarz, G. N. Duda, P. Seemann & J. Lienau
Objective: Bone morphogenetic proteins (BMPs) and growth and differentiation factors (GDFs) are important during differentiation and development. Their signalling is tightly regulated by several BMP antagonists, such as Noggin that binds to BMPs and thus inhibits the ligand receptor interaction. This[for full text, please go to the a.m. URL]