Reconstruction of a Critical Sized Segmental Bone Defect in the Ovine Tibia by Tissue Engineering Methods

J.C. Reichert, D.R. Epari, S. Saifzadeh, G.N. Duda, M.A. Schuetz & D.W. Hutmacher
Objective: Current approaches for segmental bone defect reconstruction are restricted to autografts and allografts, and metal or ceramic-based implants. Bone grafts possess osteoconductive, osteoinductive, and osteogenic properties, but face significant disadvantages. As a result, research focuses on[for full text, please go to the a.m. URL]