Increased transcript levels of the WNT-pathway genes β-catenin, GSK3β, APC and Axin2 in juvenile angiofibromas

Stefanie Weber, Vivienne Willnecker, Olaf Wendler & Bernhard Schick
Introduction: Juvenile angiofibroma is a rare fibro-vascular, mostly aggressive growing tumor occurring almost exclusively in adolescent males. In addition to the frequent finding of β-catenin mutations at the GSK3β phosphorylation site in 75% of analyzed juvenile angiofibromas, a strong[for full text, please go to the a.m. URL]