TiO2 particles increase the mutagenic risk as detected in primary human oropharyngeal epithelial cells

Johannes Brus, Kathrin Gessner, Anett Reiche, Andreas Dietz, Andreas Boehm & Gunnar Wichmann
Introduction: TiO2 is thought to be nonmutagenic but is discussed to increase inflammatory responses triggering mutagenesis. Thus TiO2 was analyzed regarding effects on micronucleus (MN) formation in our OECD-conform MN assay using primary human oropharyngeal epithelial cells (EC). Methods: After[for full text, please go to the a.m. URL]