Influence of interleukin-6 on cisplatin-induced auditory hair cell loss

Agnieszka Szczepek, Heidemarie Haput, Timo Stöver & Birgit Mazurek
Damaged auditory epithelium and consequent hearing loss is a side effect of cancer chemotherapy with cisplatin. Recent reports implicated a significant role of pro-inflammatory cytokines (IL1β, IL6 and TNFα) in the cisplatin-induced ototoxicity. The effect of two pro-inflammatory cytokines[for full text, please go to the a.m. URL]