Prognostic Relevance of Lysyl Oxidase-Expression in Oral and Oropharyngeal Squamous Cell Carcinoma (OSCC)

Andrea Albinger, Ivan Hegyi, Sandro Stöckli, Stephan Schmid & Holger Moch
Introduction: Hypoxia, the inadaquate supply of blood borne oxygen, was identified as a marker of an aggressive tumour phenotype and malignant progression. Hypoxia is associated with a poor tumour response to radiotherapy, to some chemotherapeutic agents, as well as poor outcome following surgery. Pathways[for full text, please go to the a.m. URL]