P16INK4A immunostaining patterns differentiate between the presence of high and low risk human papillomavirus types in head and neck dysplasias and papillomas

Jeroen Mooren, Elif Gültekin, Bernd Kremer, Jens Klussmann, Sandra Claessen, Annick Haesevoets, Hans Dienes, Soenke Weissenborn, Christian Huebbers & Ernst-Jan Speel
Introduction: Human papillomavirus (HPV) is a risk factor for head and neck mucosa lesions, including HPV-16 in tonsillar squamous cell carcinomas (TSCC) and HPV-6/11 in laryngeal papillomas. The aim of this study was to determine whether expression of the HPV surrogate marker p16INK4A could predict[for full text, please go to the a.m. URL]