The synthetic TLR2 agonist BPPcysMPEG leads to efficient cross-priming against co-administered and linked antigens

C. K. Prajeeth, A. C. Jirmo, J. K. Krishnaswamy, T. Ebensen, C. A. Guzman, S. Weiss, H. Constabel, R. E. Schmidt & G. M. Behrens
The property of dendritic cells (DC) to generate effective cytotoxic T lymphocyte (CTL) responses is influenced by Toll-like Receptor (TLR) signalling. TLR ligands contain molecular signatures associated with pathogens, are being exploited as potential adjuvants, and have impact on the antigen processing[for full text, please go to the a.m. URL]