Correlations between transmitted HIV-1 drug resistance mutations and the HLA alleles of therapy-naïve HIV-patients

F. Schweitzer, S. Müller, M. Däumer, R. Kaiser, M. Oette, T. Lengauer & T. Harrer
Background: ART of HIV-1 infected patients is successful but limited due to occurrences of drug resistances mutations. In therapy-naïve patients the immune system is the main force selecting mutations allowing the virus to escape recognition by CTLs. We hypothesize that these CTL specific mutations[for full text, please go to the a.m. URL]