Detection of Mycobacterium tuberculosis using the Cepheid Xpert MTB/RIF ® Assay – a clinical validation study from Tanzania

A. Rachow, G. Rojas-Ponce, E. Saathoff, K. Reither, C. Boehme, M. Perkins, M. Hoelscher & N. Heinrich
Background: Tuberculosis (TB) control is hampered by inadequate diagnosis, especially in resource-poor countries. New, rapid and simple-to-use diagnostic tools are desperately needed. Here we evaluate the Xpert MTB/RIF® test (Cepheid, USA), a cartridge-based real-time PCR assay that automates[for full text, please go to the a.m. URL]