Reactivation of tuberculosis by Mycobacterium bovis infection at the oral mucosa under immunsuppressive treatment with TNF-alpha inhibitors

D. Ernst, F.-C. Bange, M. Rana, N. Baerlecken, F. Puls, R.E. Schmidt & M. Stoll
Background: Increased risks for infectious diseases, in particular for tuberculosis,(Tbc) has been reported in patients receiving treatment with TNF-α-inhibitors. The cytokine TNF-α plays a central role in the development and maintenance of granuloma. Activation of macrophages by specific[for full text, please go to the a.m. URL]