24-nor-ursodeoxycholic acid impairs inflammatory response and hepatic fibrosis in a murine model of Schistosoma mansoni infection

M. Sombetzki, M. Loebermann, P. Fickert, A. Fuchsbichler, C. Langner, J. Gumhold, D. Silbert, D. Riebold, M.C. Holtfreter, H. Nizze, M. Trauner & E.C. Reisinger
Objectives: Vigorous intrahepatic granuloma formation and fibrosis in response to parasite eggs specify the pathological picture of Schistosoma mansoni infection as one of the worldwide leading causes for liver fibrosis and portal hypertension. Following our previous observations that 24-nor-ursodeoxycholic[for full text, please go to the a.m. URL]