Novel mutation in YMDD motif and direct neighbourhood in a child with chronic HBV-infection and clinical lamivudine and adefovir resistance – a scholarly case

V. Schildgen, S. Ziegler, R.L. Tillmann & O. Schildgen
Context: Chronic HBV infection is a major cause of hepatocellular carcinoma (HCC) which meanwhile has become the 5th most reason for a fatal outcome of cancer. Worldwide, approximately 350 million people are chronically HBV infected and as such of risk to develop HCC. Treatment of chronic infection [for full text, please go to the a.m. URL]