Emergence of an unexpected NNRTI-Resistance pattern (K103N/Y181C) in a NNRTI-naive patient during treatment interruption after only one week of treatment with Etravirin

B. Jensen, M. Balduin, N. Sichtig, S. Reuter, R. Kaiser & D. Häussinger
Objectives: Etravirin (ETR) is reported to have a higher genetic barrier compared with former NNRTIs. Nevertheless, considering its long half-life with slowly declining drug levels, unprotected treatment interruption might induce NNRTI-resistance. We present a NNRTI-naive patient who developed NNRTI-resistance[for full text, please go to the a.m. URL]