Analysis of HIV-1-specific CTL cross-reacting with Influenza A virus in a cohort of HIV-1 infected patients

A. Hückelhoven, S. Bergmann, K. Eismann, S.M. Müller, J. Etschel, E.G. Harrer, T. Harrer & Kompetenznetzwerk HIV/AIDS
Background: Recently, it has been shown that HLA-A2 restricted HIV-1-specific CTL recognizing the p17-epitope SL9 (SLYNTVATL) may cross-react with the influenza matrix epitope IMP (GILGFVFTL; Acierno et al., J translational Med, 2003) that is a dominant influenza epitope in HLA-A2 positive patients.[for full text, please go to the a.m. URL]