Effect of tumour necrosis factor-alpha on collagen metabolism in human skin

Ursula Mirastschijski, Reinhild Schnabel, Peter Vogt & Magnus Agren
Introduction: The pro-inflammatory cytokine tumour necrosis factor-α (TNF-α) is involved in a variety of inflammatory processes in different organs. Increased TNF-α levels are accused for failure of acute wound healing in skin and intestine and of chronic skin ulcers. The mechanisms[for full text, please go to the a.m. URL]