Identification and investigation of genes implicated in abdominal aortic aneurysms

Irene Hinterseher, Robert Erdman, Kimberly Kerr, Alicia Golden, Matthew Cindric, Charles Schworer, Gabor Gäbel, Hendrik Bergert, Hans Detlev Saeger, James Elmore, David Franklin, David Carey, Gerardus Tromp & Helena Kuivaniemi
Introduction: Abdominal Aortic Aneurysms (AAA) are known to be influenced by environmental and genetic factors. The pathophysiology of AAA is characterized by degradation of extracellular matrix, loss of elastin and vascular smooth muscle cells, and local chronic inflammation. The goal of the current[for full text, please go to the a.m. URL]