Selectin binding is essential for peritoneal carcinomatosis in pancreatic cancer

Florian Gebauer, Daniel Wicklein, Maximilian Bockhorn, Kersten Peldschus, Christoph Wagener, Udo Schumacher & Jakob Izbicki
Introduction: Binding of tumor cells to selectins expressed on the luminal surface of endothelial cells is a crucial event in haematogeneous metastasis formation. We analyzed the functional role of E- and P-selectins in peritoneal dissemination of pancreatic adenocarcinoma. Materials and methods:[for full text, please go to the a.m. URL]