CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells

Claudia Rubie, Vilma Frick, Pirus Ghadjar & Martin K. Schilling
Introduction: Interactions between CXCR4 and its ligand CXCL12 have been shown to be involved in cancer progression in colorectal cancer (CRC). We performed a comparative CXCL12/CXCR4 expression analysis and assessed the effect of external CXCL12 stimulation on migration of CRC cells without and[for full text, please go to the a.m. URL]