Detection of disseminated tumor initiating cells in patients with colorectal cancer – which marker is of clinical relevance?

Mia Kim, Tanja Grimmig, Markus Frank, Natasha Frank, Christoph-Thomas Germer, Ana Maria Waaga-Gasser & Martin Gasser
Introduction: Spreading of differentiated tumor cells and tumor initiating cells (TICs) from primary tumors into the periphery may occur early during tumor progression. However, TICs could be mainly responsible for tumor relapses and metachronic metastases. This study evaluates ABCB5, a newly defined[for full text, please go to the a.m. URL]